HiSiaddi is an innovative foreign trade service provider driven by dual engines of technology transformation and foreign trade services. It has established a "1+2+3+4=1" service system and can supply glabridin sourced directly from multiple well-known original manufacturers. As a foreign trader with R&D capabilities, HiSiaddi has collaborated with factories on technology transformation and accurately captured market demands on multiple occasions, successfully addressing customers’ customized requirements for glabridin. Below is a case of HiSiaddi solving customized glabridin demands.
For more customized service solutions, please contact HiSiaddi customer service.
The cooperative client is SwissCare, a premium European enterprise specializing in high-end skincare and natural active raw materials. It focuses on organic anti-aging, soothing and repairing salon skincare products and premium daily chemical goods, with products sold to high-end European markets including Switzerland, Germany and Italy. Its end customers cover luxury beauty brands, high-end medical beauty institutions and organic skincare specialty stores.
The client adopts glabridin as the core brightening and anti-inflammatory active ingredient, complying with EU Cosmetics Regulation (EC) No 1223/2009 and Swiss cosmetic safety standards. It imposes extremely stringent requirements on raw material purity, solvent system, powder particle size, residue control and formula compatibility.
In May 2026, the client launched new product R&D and required customized high-purity glabridin. It previously contacted 3 domestic raw material manufacturers, yet none could satisfy multiple customized indicators simultaneously: conventional products had insufficient purity, excessive organic solvent residues, poor water solubility and uneven particle size distribution. Repeated sample tests failed, delaying the progress of new product R&D. The client formally entrusted HiSiaddi with the task, requiring customized formula process development, lab-scale verification and pilot mass production within 18 days, alongside complete EU compliance documents to produce exclusive customized glabridin.
1. Ultra-high purity requirement: The client demanded glabridin effective content ≥98%, while conventional industrial grades only reach 90%~94%. Ordinary purification processes struggle to further purify the product and easily cause loss of active ingredients during purification.
2. Low residue control: Stringent limits on organic solvents such as methanol and ethanol, with total residues ≤10ppm — far below general domestic standards. Conventional extraction processes fail to meet this threshold.
3. Customized water-solubility modification: The client’s products adopt water-based essence systems, requiring glabridin to dissolve rapidly in cold water with clear solutions free of precipitation. Native glabridin is highly lipophilic, which directly causes stratification and turbidity when added to formulations.
4. Customized powder particle size: Powder particle size D90≤20μm to ensure uniform compounding and emulsification in subsequent processes. Ordinary crushing equipment produces wide particle size ranges, leading to agglomeration and sedimentation.
5. Full set of supporting compliance documents: Complete English documents including EU REACH registration, full-item COA test reports, toxicological reports, non-GMO certificates and microbial test reports are required to meet European cosmetic market access rules.
HiSiaddi assembled a team of natural product purification engineers, cosmetic formulators, compliance specialists and quality control personnel, and cooperated with a leading domestic glabridin R&D and production enterprise to launch customized solutions covering five dimensions: purification process, modification treatment, particle size regulation, quality control system and compliance documentation.
· Raw material selection: Premium Xinjiang licorice roots are selected to guarantee baseline active ingredient content and reduce impurities from the source.
· Multi-stage gradient purification: Abandoning traditional single-step extraction, a combined process of supercritical CO₂ extraction, macroporous resin chromatography and recrystallization is adopted to remove polysaccharides and flavonoid impurities step by step, stably boosting the active ingredient content to 98.3%~98.7%.
· Deep residue removal: Additional vacuum low-temperature drying and inert gas purging procedures thoroughly eliminate organic solvents, with third-party testing confirming total solvent residues stably controlled at 6~8ppm to satisfy the client’s limit requirements.
Food and cosmetic-grade polyol graft modification technology is applied to optimize molecular surface polarity without damaging the active structure of glabridin. The modified product can disperse and dissolve rapidly in room-temperature water, forming a clear and transparent solution with no stratification or precipitation after 72 hours of standing, perfectly matching the client’s water-based essence formulations.
Closed dust-free production is implemented with jet milling and multi-stage precision screening equipment to strictly control particle size distribution. Finished products achieve D90=17~19μm with loose powder free of agglomeration. Powder flowability is further optimized to support smooth automatic feeding, homogenization and emulsification on the client’s production lines.
Exclusive customized batch control standards are set up, with regular sampling inspections at every working procedure from raw material incoming inspection, extraction, purification, modification and powder preparation to finished product delivery. Finished product testing covers over ten indicators including purity, solubility, particle size, solvent residues, heavy metals, microorganisms and activity stability, with inter-batch indicator deviation below 0.5% to guarantee highly consistent quality.
In accordance with EU cosmetic regulations, full English documents including COA test reports, REACH registration certificates, toxicological safety reports, microbial test reports, heavy metal test reports and production process descriptions are compiled. All document information corresponds to individual batches and can be verified on official EU platforms.
1. Lab-scale verification (8 days): Three batches of 5kg lab samples were produced. The client’s laboratory completed full-item testing, formula compatibility tests and stability tests, confirming all customized indicators met standards with excellent formulation performance, and the whitening and soothing activities remained unaffected by the process.
2. Pilot mass production (7 days): After the client confirmed the solution, a dedicated production line was launched for pilot manufacturing. HiSiaddi technical specialists were stationed on-site to supervise process parameters, yielding the first batch of 30 tons of customized glabridin.
3. Packaging & shipment: Light-proof aluminum foil vacuum packaging is adopted for light blocking, oxygen isolation and moisture resistance, meeting high-end raw material warehousing requirements. Outer packages are labeled in English with customized parameters, batch numbers, traceability codes and compliance marks, alongside the full set of compliance documents. Goods were successfully declared and shipped with zero customs clearance issues.
1. Product performance compliance: All indicators of customized glabridin fully match the client’s R&D and production requirements. The product maintains stable compatibility in water-based systems, and the texture, efficacy and shelf life of end cosmetics all meet the brand’s standards, enabling finalized formulation of new products.
2. High client recognition: The client’s R&D director stated that HiSiaddi accurately understood the customization logic of high-end cosmetic raw materials, broke through the limitations of conventional processes, fulfilled all technical indicators and provided a complete EU compliance system, eliminating multiple concerns over overseas procurement.
3. Deepened binding cooperation: The client terminated cooperation with original suppliers and designated HiSiaddi as exclusive customized supplier for glabridin, signing an annual procurement agreement with steadily rising annual purchase volumes. For subsequent new product development, the client continues to entrust HiSiaddi with customized active ingredient development, process optimization and compliance consulting services.
Overseas mid-to-high-end cosmetic brands purchasing glabridin primarily prioritize high purity, low residues, formula compatibility, precise dosage forms and international compliance, unlike low-end clients who only focus on basic content and pricing.
In this service, relying on natural product purification technology, cosmetic application experience and EU cosmetic compliance capabilities, HiSiaddi built a full industrial chain covering "demand decomposition — process customization — test verification — mass production implementation — compliant delivery". It resolved technical bottlenecks while avoiding overseas market access risks, aligning with core demands of high-end clients for quality, stability and professionalism, and ultimately secured long-term strategic cooperation.
For more customized service solutions, please contact HiSiaddi customer service.
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