HiSiaddi is an innovative foreign trade service provider driven by dual engines of technology transformation and foreign trade services. It has established a "1+2+3+4=1" service system and can supply glabridin sourced directly from multiple well-known original manufacturers. As a foreign trader with R&D capabilities, HiSiaddi has collaborated with factories on technology transformation and accurately captured market demands on multiple occasions, proposing formula optimization and application improvement solutions for glabridin products. Below is a case of HiSiaddi’s consulting service on glabridin formula optimization.
For more formula optimization consulting services, please contact HiSiaddi customer service.
The cooperative client is Lumina Beauty, a renowned premium organic beauty brand based in Italy, specializing in brightening essences and repairing creams for salon and light luxury retail channels. All products comply with EU cosmetic regulations and organic certification standards, sold to major European markets including Italy, France and Spain. The brand has long adopted 98% high-purity glabridin as its core brightening active ingredient, leveraging its mild and efficient properties to build star product lines.
In May 2026, after bulk purchasing conventional high-purity glabridin, the client encountered multiple technical issues during formula testing and industrial manufacturing: turbid and layered materials, active ingredient attenuation during storage, discoloration under high-temperature processing, and powder agglomeration during feeding. These problems delayed new product formulation and forced production line speed reduction, hurting both production capacity and product quality. The client’s internal formulation team adjusted parameters repeatedly yet failed to completely resolve the issues, and subsequently entrusted HiSiaddi with full-process technical diagnosis, formula optimization, production process rectification and on-site implementation guidance, requiring all issues to be fully resolved within two weeks to restore normal production and guarantee long-term product stability.
Combining the client’s two core dosage forms (water-based essences and creams) and automated production line operating conditions, HiSiaddi identified four critical problems via sample testing, on-site condition review and formula disassembly:
1. Insufficient water solubility leading to material stratification and turbidity Glabridin is inherently lipophilic, while the client’s formulas are water-dominant with only a small amount of alcohols for solubilization. Microcrystalline precipitation occurs after 48 hours of standing, making transparent essences lose clarity and failing to meet appearance standards for premium products.
2. Poor photo-thermal stability causing severe active ingredient attenuation The raw material is sensitive to light and high temperatures. The client’s emulsification process operates at elevated temperatures without protective treatment in formulas, resulting in a 12% drop in glabridin activity after one month of room-temperature storage, significantly weakening brightening efficacy and failing shelf-life requirements.
3. Incompatible ingredients triggering system discoloration The formula compounded vitamin C derivatives, which accelerate oxidation reactions when coexisting with glabridin, gradually turning creams and essences yellow and severely damaging product appearance and brand reputation.
4. Poor powder fluidity causing agglomeration during production feeding Uneven particle size distribution and strong hygroscopicity of raw material powder lead to caking and wall adhesion during automated negative-pressure feeding, causing raw material loss and uneven distribution of active ingredients across batches with obvious quality discrepancies.
HiSiaddi formed a technical team of cosmetic application engineers, natural ingredient R&D specialists and production process specialists to conduct targeted optimization covering four dimensions: raw material adaptation, formula system, production parameters and post-storage management. The solutions comply with EU regulatory requirements and the client’s existing production line conditions without large-scale equipment renovation.
Single alcohol solubilization is replaced with a composite system of polyols and mild nonionic solubilizers, enhancing glabridin dispersion stability without skin irritation or violation of organic formulation concepts. The client is advised to adjust feeding sequence: fully dissolve glabridin in a mixed solvent of propylene glycol and 1,3-butanediol before slowly adding to the water phase under stirring. After optimization, transparent essences remain clear without precipitation or stratification for 90 days of standing.
Two-pronged protection is deployed against glabridin’s photosensitive and heat-sensitive properties:
1. Add food-grade special composite antioxidants for cosmetics to block oxidation of phenolic hydroxyl groups in formulas;
2. Adjust production processes to lower emulsification and homogenization temperature below 60℃ and shorten high-temperature exposure time, paired with light-proof packaging materials. After 3 months of accelerated aging testing at 40℃, glabridin activity attenuation is controlled within 3%, fully meeting the 24-month shelf-life standard.
Two actionable solutions are provided to address yellowing oxidation between glabridin and vitamin C derivatives:
1. Staggered feeding: add the two active ingredients at high and low temperature stages separately to prevent direct contact under high heat;
2. Replace with stable encapsulated vitamin C derivatives to eliminate oxidation reactions fundamentally.
The client selected the staggered feeding solution aligned with its product line positioning, and finished products no longer yellow or discolor after long-term storage post rectification.
Cooperate with raw material manufacturers to conduct mild surface hydrophobic modification on glabridin, reducing hygroscopicity and boosting powder fluidity without altering purity or activity. Meanwhile, HiSiaddi guided the client to adjust feeding equipment wind speed and stirring rotation speed, and add a pre-mixing procedure. After rectification, powder feeding occurs without agglomeration or wall adhesion, uniformity of active ingredient mixing is greatly improved, and inter-batch content deviation is controlled within 0.4%, restoring production efficiency to normal levels.
HiSiaddi engineers visited the client’s production workshop to deliver hands-on training for formulators and operators, standardizing parameters including temperature, rotation speed and feeding sequence for each procedure and compiling written operating instructions to ensure long-term stable execution of optimized solutions.
1. Lab batch verification: Three batches of lab production were completed per optimized solutions, with all indicators including appearance, solubility, active content, stability and uniformity passing testing. The client’s formulation team confirmed the feasibility of the solutions.
2. Full-scale resumed production: The client fully adopted new formulas and production parameters, restoring full-load operation of the entire production line. Continuous manufacturing of 15 batches maintained stable product quality with no recurrence of stratification, discoloration or active attenuation issues.
3. End-user feedback: Post-launch consumer feedback highlighted superior texture and efficacy compared with previous versions, sustaining high product reputation.
1. Complete resolution of technical problems: All four core technical challenges were fully eliminated. The client utilized existing raw material inventory efficiently, resumed scheduled progress for new product R&D, and reduced production costs and raw material losses simultaneously.
2. Deep client recognition: The client’s technical lead commented that HiSiaddi not only resolved urgent production crises but also provided long-term formula application recommendations based on the physicochemical properties of glabridin, demonstrating professionalism far exceeding ordinary trading service providers.
3. Upgraded long-term cooperation: The client designated HiSiaddi as core supplier and exclusive technical service partner for glabridin. All subsequent brightening new product formulation development involves advance consultation with HiSiaddi for raw material adaptation and process prediction, alongside expanded annual purchase volumes.
For overseas mid-to-high-end beauty brands using glabridin, difficulties extend beyond raw material purity, focusing more on three major application segments: formula compatibility, production adaptability and long-term stability. Such clients prioritize complete technical supporting services rather than simply purchasing raw materials at low prices.
In this service, HiSiaddi developed customized rectification solutions based on glabridin’s inherent physicochemical properties, matching the client’s dosage forms, equipment and formula systems while balancing efficacy, sensory experience, production efficiency and compliance requirements. Full-chain technical services solidified cooperation foundations and met core demands of high-end beauty clients for quality and professionalism.
For more formula optimization consulting services, please contact HiSiaddi customer service.
+86-13120989737 
info@hisiaddi.com 
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