HiSiaddi is an innovative foreign trade service provider driven by both technology transformation and export business. We have established a "1+2+3+4=1" service system and can supply original factory products of multiple well-known sophorolipid brands. As a technology R&D-oriented foreign trader, HiSiaddi has repeatedly resolved customized sophorolipid product demands for clients through technological transformation cooperation with manufacturers and precise insight into market demands. Below is a case of HiSiaddi addressing customized sophorolipid requirements.
Contact HiSiaddi customer service for more customized service inquiries.
The client is NATURESENCE, a high-end German natural skincare brand focusing on premium organic, zero-irritation, biodegradable skincare lines sold to high-end beauty markets in Germany, Switzerland, Austria and other European regions, targeting sensitive skin and organic skincare consumers. For this project, they required customized high-purity sophorolipids for premium repair serums, sensitive-skin cleansers and organic body lotions with core specifications as follows:
100% acid-type sophorolipids (lactone-free), purity ≥95%, 100% bio-based content, palm oil-free, free of synthetic preservatives and heavy metals.
Low surface tension (≤32 mN/m), high emulsification stability, mild bacteriostasis, zero skin irritation.
Compliant with EU ECOCERT organic certification, CosIng cosmetic safety standards, REACH registration, OECD biodegradability ≥92%.
Flexible small-batch production (minimum order 50kg per batch), proprietary fermentation strains, traceable production records, English COA and full-item test reports.
This was the client’s first time customizing sophorolipids in China. After contacting 3 manufacturers, none could satisfy their four core requirements: high-purity acid-type formula, palm oil-free formula, organic certification and flexible customization. Most manufacturers only produced acid-lactone mixtures (70/30 ratio) with purity ranging from 80% to 85%, used palm oil as raw material, lacked organic certifications, only supported large-batch production (minimum 500kg), suffered insufficient technical capacity, slow response to customization and incomplete compliance documents. As a result, the client failed to match raw materials with their premium skincare formulas, faced supply disruption risks and failed European certification audits. They therefore entrusted HiSiaddi with full-process customized development to resolve technical and production challenges and deliver tailor-made finished products.
1. Difficulty in customizing component structure: Hard to achieve single acid-type formula with high purity The client required 100% acid-type sophorolipids with zero lactone residue and purity above 95%. Fermentation outputs from ordinary manufacturers are mixtures of 70% acid-type and 30% lactone-type sophorolipids. Their insufficient separation and purification technology only delivers a maximum purity of 85% with lactone residue ≥12%, failing to meet the zero-irritation and high-activity standards for sensitive-skin skincare products.
The client demanded palm oil-free raw materials with 100% non-food carbon sources (glucose + waste rapeseed oil). Most manufacturers adopted palm oil as hydrophobic carbon sources to cut costs, conflicting with European sustainable development trends and palm oil-free consumer preferences.
1. Difficulty balancing green low-carbon fermentation and flexible customized production The client required eco-friendly low-energy fermentation with zero harmful emissions and traceable carbon footprints. Conventional manufacturers ran fermentation at high temperatures (32–35°C) with high energy consumption, substandard wastewater treatment and no carbon footprint accounting.
The client needed flexible small-batch production (50kg minimum per batch), quick production changeovers and fermentation with proprietary strains. However, factory production lines were designed for mass production (minimum 500kg) with long 15-day changeover cycles and single fixed strains, incompatible with customized orders.
1.
Barriers in compliance certification: Lack of organic certification and EU-standard documents The client needed ECOCERT organic certification, CosIng filing, REACH registration, OECD 301B biodegradability reports and full heavy metal/microbiological test records. Ordinary manufacturers held no organic certifications, only provided industrial-grade COAs, issued SDS non-compliant with EU standards and lacked biodegradability test reports, making it impossible to pass European beauty safety audits.
2.
3.
Technical communication barriers: Poor coordination between formula adaptation and performance optimization The client’s German in-house formulation experts required in-depth technical coordination, English technical documents and customized performance testing (skin irritation, emulsification stability, bacteriostatic rate). Factory technicians had limited English proficiency and lacked professional testing equipment, unable to deliver customized test data. This prolonged formula adaptation cycles, led to substandard performance and repeated trial-and-error processes.
4.
HiSiaddi assembled a dedicated team consisting of fermentation technical specialists, separation and purification engineers, cosmetic regulatory specialists and organic certification consultants with German language technical support. We adopted a six-step solution: Strain Customization → Fermentation Process Optimization → Separation & Purification Upgrade → Green Production Control → Compliance Certification Handling → Formula Adaptation Testing, completing small-batch trial production in 28 days and stable mass production in 60 days.
· Strain Screening & Modification: Cooperated with the Fermentation Engineering Laboratory of Jiangnan University to perform gene editing on Candida bombicola via knockout of the SBLE lactonase gene, developing proprietary strain HS-SL001 that produces 100% acid-type sophorolipids with no lactone residue.
· Optimized Carbon Source: Adopted dual carbon sources (glucose for hydrophilic segment + waste rapeseed oil for hydrophobic segment), palm oil-free, 100% bio-based and carbon-neutral, complying with European sustainability standards.
· Small-Scale Verification: 5L fermenter lab trials achieved 100% acid-type ratio, total purity of 96.2%, surface tension of 31.8 mN/m and biodegradability of 94.5%, fully meeting all specifications.
· Optimized Process Parameters: Lowered fermentation temperature from 33°C to 26°C, cutting energy consumption by 35%, reducing byproducts and improving strain activity. Fine-tuned pH (5.8–6.2), dissolved oxygen (DO ≥30%) and stirring speed, shortening fermentation cycles to 72 hours and boosting yield to 220g/L.
· Retrofitted Flexible Production Line: Coordinated partner factories to upgrade a 100L pilot production line supporting minimum orders of 50kg per batch with 7-day production changeovers, independent dedicated fermenters and full sterile control to satisfy small-batch customization demands.
· Green Production Management: Fermentation wastewater underwent membrane filtration and biodegradation treatment for recycling; full carbon footprint calculation was performed to issue PAS 2050 carbon footprint reports in line with European ESG requirements.
· Upgraded Purification Technology: Deployed two-stage ultrafiltration (30kDa → 10kDa), pH gradient extraction and vacuum low-temperature drying to remove bacterial cells, polysaccharides, proteins, pigments and residual oils.
· Precise Purity Control: Online monitoring of purity, acid-type ratio and impurity content at every purification stage. Final products featured 100% acid-type content, total purity ≥96%, moisture ≤0.5%, undetected heavy metals (lead/cadmium/mercury/arsenic) and total microbial count <10 CFU/g.
· Stability Testing: 6-month accelerated stability testing at 40°C showed purity decline <0.8%, no delamination or peculiar odors, matching the long shelf-life requirements of premium skincare products.
· ECOCERT Organic Certification: Compiled strain source documents, carbon source certificates, production records and test reports, and entrusted ECOCERT China to conduct audits, obtaining organic certification within 21 days with labels certifying 100% bio-based and palm oil-free properties.
· EU Compliance Document Processing:
1. Compiled 16-chapter English SDS compliant with REACH Annex II + CLP, supplemented with EC numbers, CAS numbers, SVHC non-detection statements and EU emergency contact numbers.
2. Completed REACH registration (annual output ≥1 ton), providing registration certificates and dossier summaries.
3. Commissioned SGS testing to issue OECD 301B biodegradability reports (94.5%), full heavy metal/microbiological test reports and zero skin irritation human patch test reports.
· Customized English COA: Each batch shipped with an English Certificate of Analysis listing strain numbers, fermentation parameters, purification records and full test data for full traceability, meeting European beauty audit standards.
· Customized Performance Testing: Completed tests as per client formula requirements, including emulsification stability (no delamination after 5 cold-heat cycles), bacteriostatic rate (≥99% against Propionibacterium acnes and Candida albicans), zero skin irritation human patch tests and essential oil solubilization capacity (≥15% solubilization rate), all passing specifications.
· In-Depth Technical Coordination: HiSiaddi German-speaking technical specialists held weekly video conferences with the client’s German formulation team, synchronizing fermentation data, purification reports and performance test results, and providing English technical whitepapers, application guidelines and formula recommendations to rapidly resolve formula adaptation issues.
· Small-Batch Trial Delivery: 50kg initial trial batch delivered within 28 days, featuring 100% acid-type content, 96.5% purity and complete organic certifications with fully compliant performance. The client’s laboratory successfully validated the formula for repair serum sample development.
· Confirmed Mass Production Scheme: Stable mass production launched within 60 days with flexible batch output ranging from 50kg to 500kg, catering to both small-batch new product R&D and medium-batch commercial manufacturing demands.
· Dedicated Quality Control System: Established full-process QC standards covering strain cultivation, fermentation, purification, packaging and delivery, with batch retention testing, archived data and full traceability to guarantee consistent quality across batches.
· Customized Packaging: Food-grade sterile 25kg plastic drums labeled in English with ECOCERT organic logos, GHS non-hazardous product markings, batch numbers and expiry dates, compliant with EU transportation and warehousing regulations.
1.
Sample Review & Confirmation HiSiaddi supplied three batches of trial samples alongside full English technical documents, organic certification reports and performance test data. Joint audits by the client’s German headquarters formulation and compliance teams confirmed full compliance with all requirements with zero objections.
2.
3.
Initial Trial Batch Delivery The 50kg customized sophorolipid trial batch delivered in 28 days was used for premium repair serum sample development. The raw material delivered perfect formula compatibility, zero skin irritation in dermatological testing and remarkable soothing anti-inflammatory repair effects. Consumer testing of samples achieved a 98% satisfaction rate.
4.
5.
Stable Mass Production & Long-Term Supply Stable mass production launched within 60 days; the client placed an initial 200kg mass production order for sensitive-skin cleansers and organic body lotions. Subsequent monthly procurement volume ranged from 300kg to 500kg, generating annual procurement turnover of 1.2 million EUR and establishing HiSiaddi as their core raw material supplier.
6.
7.
Client Feedback German R&D Director commented: “HiSiaddi not only realized customized production of 100% acid-type high-purity sophorolipids for us, but also resolved all challenges including green fermentation, organic certification and formula adaptation. Their technical expertise, rapid response and efficient communication make them our most trusted Chinese customized raw material partner, fueling outstanding market performance of our organic skincare line across Europe.”
8.
The core challenge of this customization project lay in the ultra-stringent requirements of high-end natural skincare brands for sophorolipid component structure, purity, eco-friendly manufacturing, organic certification and flexible small-batch production. Conventional domestic manufacturers suffered insufficient technical capacity, outdated processes, weak compliance awareness and lack of customized service capabilities, making them unable to meet such demands.
HiSiaddi’s core competitive strengths lie in integrated technical capabilities, customized service capacity, EU compliance expertise and cross-cultural communication skills:
· Technical Side: Cooperated with universities to conduct gene editing strain modification and optimize fermentation & purification processes to achieve 100% acid-type content, purity above 96% and green low-carbon manufacturing.
· Production Side: Retrofitted flexible production lines to support small-batch customization, rapid changeovers and dedicated independent production control.
· Compliance Side: Delivered one-stop organic certification and EU compliance document services fully aligned with European premium beauty standards.
· Service Side: German-language technical coordination, in-depth formula adaptation and full traceable quality control to eliminate cross-cultural technical communication barriers.
For overseas mid-to-high-end brands sourcing fine chemical raw materials in China, partnering with a foreign trade supplier equipped with R&D capabilities, customized production capacity, EU compliance experience and professional cross-cultural services is critical to delivering tailor-made products, ensuring consistent quality, meeting international standards and expanding high-end markets. Leveraging integrated strengths in technology, service and compliance, HiSiaddi stands as the preferred customized raw material partner for overseas high-end beauty, pharmaceutical and green daily chemical enterprises.
Contact HiSiaddi customer service for more customized service inquiries.
+86-13120989737 
info@hisiaddi.com 
English
