SHANGHAI HI SILICON TECHNOLOGY CO., LTD.
SHANGHAI HI SILICON TECHNOLOGY CO., LTD.

Licorice Extract: Major Process Innovations & Breakthroughs of Top Market Share Brands in China & Global Markets

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    As a new-type foreign trade service provider driven by technological transformation and foreign trade services, HiSiaddi has established a "1+2+3+4=1" service system and can supply original factory goods from multiple well-known brands of Licorice Extract.

    As an R&D-capable foreign trade enterprise, unlike single-brand manufacturers that only promote their proprietary technology, we objectively analyze multiple top market-share domestic and international brands and share their landmark process innovations and technical breakthroughs to deliver authentic, up-to-date market intelligence for buyers.

    For more comprehensive and valuable Licorice Extract market insights, contact HiSiaddi customer service.

    I. Technical Breakthroughs & Product Indicator Upgrades of China’s Top 5 Licorice Extract Export Brands

    (Gansu Fanzhi Pharmaceutical, Ningxia Yipin Biological, Xinjiang Yitai Biological, Jiangsu Caiwei Biological, Huashidan Pharmaceutical)

    (1) Gansu Fanzhi Pharmaceutical: Industrial Scale 定向 Purification Breakthrough, Mass Production of Ton-Scale High-Purity Glabridin & Residual-Alcohol-Free Dipotassium Glycyrrhizinate

    1. Breakthrough Details: Self-developed resin directional enrichment and purification technology commissioned the world’s first ton-scale industrial production line for glabridin. A closed-loop pure water extraction process replaces ethanol solvent methods for cosmetic-grade dipotassium glycyrrhizinate, with full recovery of mother liquor and resource utilization of by-product licorice fiber.

    2. Key Indicator Improvements: ① Glabridin purity ≥90.2% (traditional craft ≤72%); raw material extraction yield increased from 0.1% to 1.25%, breaking overseas monopolies on high-priced supplies. ② Dipotassium glycyrrhizinate ethanol residual ≤0.3%, ammonium residual ≤0.006%, lead heavy metal ≤0.3ppm, arsenic ≤0.1ppm, exceeding EU Cosmetic Regulation EC1223 new standards. ③ Per-ton production cost reduced by 26.7%; wastewater discharge cut by 42%.

    3. End Application Fields: High-end whitening skincare, sensitive skin repair raw materials, topical anti-inflammatory pharmaceutical preparations.

    (2) Ningxia Yipin Biological: Continuous Countercurrent Extraction + Membrane Coupling Refinement Breakthrough, Large-Scale Production of High-Yield Food-Grade Glycyrrhizin

    1. Breakthrough Details: Full-process low-temperature continuous countercurrent extraction paired with complete nanofiltration impurity separation equipment eliminates traditional intermittent alcohol precipitation, supported by fully automated closed production lines.

    2. Key Indicator Improvements: ① Total glycyrrhizic acid extraction yield reaches 91.6% (industry standard range: 73%–79%). ② Glycyrrhizin sweetness stabilized at 88 times sucrose, ash content ≤0.4%, all 217 pesticide residues undetected. ③ Active ingredient retention ≥95% after 30-minute high-temperature sterilization at 125°C.

    3. End Application Fields: Sugar-free beverages, baked goods, natural sweeteners and antioxidants for meat products.

    (3) Xinjiang Yitai Biological: Enzymatic Cell Wall Breaking Coupled with Subcritical Extraction Breakthrough, Mass Production of Low-Impurity High-Purity Pharmaceutical Glycyrrhetinic Acid

    1. Breakthrough Details: Compound cellulase low-temperature cell wall destruction paired with subcritical CO₂ extraction replaces traditional strong acid hydrolysis processes, eliminating highly acidic wastewater discharge.

    2. Key Indicator Improvements: ① 18β-Glycyrrhetinic acid content ≥98.5%, total impurity glycyrrhizic acid & liquiritin <0.2%. ② Organic solvent residual <20ppm, Aflatoxin B1 undetected, compliant with EP and USP pharmaceutical pharmacopoeia standards.

    3. End Application Fields: Liver-protective API, anti-inflammatory dietary supplement capsules, pharmaceutical intermediates.

    (4) Jiangsu Caiwei Biological: Low-Temperature Microcapsule Encapsulation Breakthrough, Mass Production of High-Temperature Resistant Water-Soluble Licorice Antioxidants

    1. Breakthrough Details: In-situ fluidized bed encapsulation modification technology using plant polysaccharides to target and wrap licorice flavonoid active components.

    2. Key Indicator Improvements: ① Flavonoid activity retention rate reaches 91.3% after 180°C high-temperature processing (uncoated raw powder only 56%). ② Cold water solubility elevated to 4.2%, aqueous solutions remain clear without precipitation for 72 hours at ambient temperature. ③ Formula addition dosage reduced by 32% to achieve equivalent antioxidant efficacy.

    3. End Application Fields: Dairy products, functional meal replacement powders, anti-corrosion ingredients for high-temperature puffed snacks.

    (5) Huashidan Pharmaceutical: Targeted Glycyrrhizic Acid Molecular Modification Breakthrough, Industrialized Production of High-Activity Modified Glycyrrhizic Acid Derivatives

    1. Breakthrough Details: Joint laboratory collaboration with the Chinese Academy of Sciences applies biocatalytic targeted modification to glycyrrhizic acid molecular structures, with industrialized production of modified derivatives protected under US invention patents.

    2. Key Indicator Improvements: ① In vitro anti-inflammatory activity 3.8 times higher than natural glycyrrhizic acid. ② No flocculation or precipitation across pH 3.0–9.0 full acid-base spectrum, long-term stable compatibility with calcium, zinc and other trace mineral elements.

    3. End Application Fields: Intestinal health feed additives for livestock and poultry, functional pet nutrition products.

    II. Technical Breakthroughs & Product Indicator Upgrades of Global Top 5 Overseas Brands

    (Germany Norevo, US Mafco, Japan Maruzen Pharmaceutical, France Naturex, Iran ASEH Licorice)

    (1) Germany Norevo: Microchannel Continuous Synthetic Refinement Breakthrough, Commercialized Low-Sodium Stable Pharmaceutical Ammonium Glycyrrhizinate

    1. Breakthrough Details: Microchannel millisecond temperature-controlled chelating salt-forming technology precisely regulates ammonium binding ratios; multi-stage simulated moving bed chromatography removes free sodium salt impurities.

    2. Key Indicator Improvements: ① Free sodium ≤0.12% (conventional products ≥1.3%). ② Solution stability maintained for 120 days without precipitation across pH 4.2–7.8. ③ Oral preparation dissolution rate increased by 27%.

    3. End Application Fields: European and American prescription cough formulations, sustained-release tablet APIs.

    (2) US Mafco: Organic Cold Infusion Full Physical Extraction Breakthrough, Mass Production of USDA Organic Clean-Label Licorice Extract

    1. Breakthrough Details: Ambient-temperature pure water low-temperature immersion with fully physical processing, no chemical extraction additives or alcohol solvents, paired with traceable organic licorice planting bases.

    2. Key Indicator Improvements: Undetectable organic solvents and chemical processing aids, eligible for EU ECOCERT and US USDA organic clean labeling; natural sweet flavor impurities reduced by 75% with no bitter licorice off-notes.

    3. End Application Fields: Organic infant complementary food, natural herbal oral liquids, organic confectionery.

    (3) Japan Maruzen Pharmaceutical: Nano Jet Milling Modification Breakthrough, Mass Production of High-Absorption Nano-Scale Licorice Extract

    1. Breakthrough Details: Low-temperature inert gas nano ultrafine pulverization achieves powder median particle size ≤150nm.

    2. Key Indicator Improvements: In vitro gastrointestinal absorption rate increased by 59%; formula feeding dosage reduced by 29% for health supplements; powder angle of repose 31°, eliminating blockages in fully automated feeding systems.

    3. End Application Fields: High-end throat-soothing soft candies, sublingual herbal powder formulations.

    (4) France Naturex: Microbial Bioconversion Debittering Breakthrough, Commercialized Low-Irritation Food-Grade Modified Glycyrrhizin

    1. Breakthrough Details: Targeted bioconversion using Aspergillus niger biologically removes bitter secondary licorice alkaloids, replacing chemical alkali refining debittering processes.

    2. Key Indicator Improvements: Product bitterness reduced by 83%, eliminating the need for additional sweet masking agents; drastically lowered oral and gastrointestinal irritation for low-sensitivity formulations.

    3. End Application Fields: Children’s functional beverages, sugar-free sparkling drinks.

    (5) Iran ASEH Licorice: Saline-Alkali Resistant Agricultural Modification Process Breakthrough, Mass Production of Chelated Agricultural Licorice Antibacterial Extract

    1. Breakthrough Details: In-situ chelation modification with small-molecule organic acids optimizes molecular structure for hard water tolerance.

    2. Key Indicator Improvements: Chelation retention rate ≥89% after 80 days in pH 9.1 saline-alkali water fertilizer systems, no precipitation or activity loss in high-calcium hard water environments; expanded antibacterial spectrum with 41% higher inhibition rate against soil-borne fungi.

    3. End Application Fields: Foliar antibacterial fertilizers for fruit & vegetable crops in saline-alkali land, additive for greenhouse hydroponic nutrient solutions.

    III. Direct Benefits Delivered by All Technical Breakthroughs to Overseas Buyers & End Customers

    (1) Overseas Buyers (Food Ingredient Factories, Cosmetic Manufacturers, Pharmaceutical Enterprises, Feed Producers)

    1. Procurement Cost Savings: Domestic Chinese new processes boost extraction yields and realize resource utilization of by-products, reducing raw material prices for equivalent-grade products by 17%–24% versus overseas brands. High-activity modified ingredients cut formula addition dosages, simultaneously lowering auxiliary material, packaging, ocean storage and logistics expenses.

    2. Production Compatibility: Water-soluble, high-temperature resistant and anti-precipitation modified raw materials integrate directly into existing wet batching, high-temperature granulation and tableting production lines without equipment retrofits; optimized flowability powders reduce production feeding scrappage losses by over 14%.

    3. Customs & Compliance Advantages: Ultra-low pesticide residues, heavy metals and solvent residuals align with 2026 EU REACH, US FCC and Cosmetic EC new regulations, mitigating risks of customs inspection detention and finished product recalls. Top domestic brands hold pre-completed FDA GRAS and EU CEP filings, shortening clients’ new product compliance declaration cycles.

    4. Stable Supply Chains: Multiple newly commissioned intelligent continuous extraction production lines in China offset overseas manufacturers’ peak-season capacity shortages, enabling buyers to dual-source orders from domestic and international suppliers to avoid single-origin raw material supply disruptions and production delays.

    (2) End Consumer Brands & End Consumers

    1. Product Differentiation: Organic clean-label, low-bitterness, high-absorption nano and water-soluble innovative raw materials empower end brands to launch differentiated products including organic food, low-sensitivity children’s beverages and high-end whitening skincare, boosting end-product market premium margins.

    2. Quality Optimization: Low-impurity, low-off-flavor raw materials reduce required levels of artificial flavors and preservatives, aligning with global clean-label ingredient consumption trends. Modified sustained-release raw materials enhance finished product storage stability, cutting active ingredient degradation rates by over 30% within shelf life.

    3. Expanded Product Categories: Water-solubility technology overcomes the traditional limitation of poor licorice extract solubility in acidic liquids, enabling mass production of previously unfeasible new product lines such as transparent acidic beverages and liquid nutritional tonics.

    For more comprehensive and valuable Licorice Extract market insights, contact HiSiaddi customer service.


    References
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